“Such strategies for the opening of arenes combine the virtues of the increased reactivity by a dearomatisation with the ability to entirely remodel aromatic rings
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“he now hopes to use ARO with ‘more challenging molecular skeletons’ , such as unactivated benzene rings, as well as finding new practical applications of these reactions
“Our ARO products feature conjugated double bonds analogous to 1,3-butadiene
“Our main challenge centred on the key nitrosophenol intermediate
“striking and thought-provoking masterclass of this new realm of synthesis
“the team eventually isolated the compound by altering the reaction conditions so that there were no nucleophiles present
“meant to evoke existing without the concreteness of space
“It takes a genuine surprise to create a catalyst.
“AI is changing the balance between attackers and defenders, and that models make it faster and cheaper to search large codebases for weaknesses